Jenereta Wapadera wa Nayitrogeni Kuti Agwiritse Ntchito Pamakampani Opanga Mankhwala

Zida za nayitrogeni wamankhwala (nitrogen purity 99.99%) ndi jenereta ya nayitrogeni yamankhwala yomwe idapangidwa potengera kafukufuku wa akatswiri komanso chitukuko cha majenereta a nayitrogeni m'zaka zaposachedwa, molingana ndi miyezo ya GMP. Poyerekeza ndi chitsulo yamphamvu ya nayitrogeni (kapena nayitrogeni wamadzi), imakhala ndi ndalama zochepa zogwirira ntchito, kuyeretsedwa kwa nayitrogeni, komanso kugwira ntchito kosavuta.

Singano zamadzi (monga penicillin) ndi njira zazikulu zolowetsera (monga ma amino acid) zomwe nthawi zambiri zimakhala ndi okosijeni zimafunika kudzazidwa ndi nayitrogeni kuti zitetezeke, apo ayi yankho lamankhwala limakhala lopangidwa ndi okosijeni mosavuta posungira, zomwe zimapangitsa kuwonongeka. Nthawi zambiri, musanayambe kulongedza, njira yodzaza nayitrogeni imagwiritsidwa ntchito (kapena kutulutsa kwa nayitrogeni kamodzi) kuti muchepetse kuchuluka kwa okosijeni mu ma ampoules kapena mabotolo olowetsedwa mpaka pansi pa 0.5%, kulola kuti mankhwalawa asungidwe kwa nthawi yayitali. Pakalipano, zida zogulidwa ndi opanga ambiri ndi za 5-20m3 / h, ndi chiyero cha 99.99%. Kusiyana pakati pa jenereta ya nayitrogeni yamankhwala ndi zida zina za nayitrogeni ndikuti malinga ndi muyezo wapadziko lonse lapansi wa GMP mumakampani opanga mankhwala, magawo omwe amalumikizana ndi mankhwala kapena mankhwala amadzimadzi amapangidwa ndi chitsulo chosapanga dzimbiri ndipo amafuna kutsekereza. Zipangizozi ziyenera kupangidwa ndi chitsulo chosapanga dzimbiri ndipo chipangizo choyezera chotchinga chiyenera kuikidwa pamalo otulutsira nayitrogeni wa zida. Komanso, chifukwa mafakitale opanga mankhwala ali ndi zofunika kwambiri pazida zonse, nthawi zambiri amasankha masinthidwe apamwamba kwambiri.

M'mafakitale opangira zinthu zopangira, mpweya wa nayitrogeni umafunikanso kuti mutetezeke mumlengalenga, ndipo njira yogwiritsira ntchito mpweya wa nayitrogeni ndi yofanana ndi ya zomera zabwino za mankhwala. Chiyero chokhazikika ndi 99% -99.9%, koma ndalama zomwe zimagwiritsidwa ntchito zimasiyana malinga ndi kukula kwa fakitale, koma ndi zazikulu kwambiri poyerekeza ndi kuchuluka kwa mankhwala opangira mankhwala a nayitrogeni.

Pamene mpweya mu kupsyinjika mwa kuyeretsedwa ndi kuyanika, Base pa Aerodynamics, nayitrogeni ndi mpweya mu mlengalenga mu zeolite molecular sieve (ZMS) pa Pressure swing adsorption adzakhala ntchito zosiyanasiyana kufala mlingo mwa adsorption wa asafe. Oxygen mu sieve ya carbon molecular pamwamba pa mlingo wa kufalikira ndi wapamwamba kuposa nayitrogeni. Pamene adsorption inalibe muyeso, mpweya unkatengedwa ndi mpweya wa carbon molecular sieve wochuluka, ndipo nayitrogeni inayikidwa ndikulemeretsedwa mu gawo la mpweya kuti ikwaniritse kulekanitsa kwa mpweya ndi nayitrogeni.